![]() ![]() Progenitor cell, such as hematopoietic stem cell and mesenchymal stem cell They give rise to a limited range of cells within a tissue type. It can even give rise to an entire functional organism.Įmbryonic stem cell, Callus They can give rise to all tissue types, but cannot give rise to an entire organism. Zygote, Spore, Morula It has the potential to give rise to any and all human cells, such as brain, liver, blood or heart cells. ![]() Have been identified in almost all caner/tumor, such as Acute Myeloid leukemic SCs (CD34 +/CD38 -), Brain tumor SCs (CD133 +), Breast cancer SCs (CD44 +/CD24 - ), Multiple Myeloma SCs (CD138 +), Colon cancer SCs (CD133 +), Liver cancer SCs (CD133 +), Pancreatic cancer SCs (CD44 +/CD24 +), Lung cancer SCs (CD133 +), Ovary cancer SCs (CD44 +/CD117 +), Prostate cancer SCs ( CD133 +/CD44 +), Melanoma SCs (CD4 +/CD25 +/FoxP3 +), Gastric cancer SCs (CD44 +).Ī type of pluripotent stem s artificially derived from a non-pluripotent cell, typically an adult somatic cell, by inducing a "forced" expression of specific genes. Mesodermal Origin: Hematopoietic SCs, Mesenchymal Stroma SCs, Mesenchymal SCs, mesenchymal precursor SCs, multipotent adult progenitor cells, bone marrow SCs, Fetal somatic SCs, Unrestricted Somatic SCs, Cardiac SCs, Satellite cells of muscleĮctodermal Origin : Neural SCs,Skin SCs,Ocular SCs They provide the source for stem cells without an ethnic conflict.Īre pluripotent stem cells derived from the inner cell mass of the blastocyst, an early-stage embryo.Įndodermal Origin: Pulmonary Epithelial SCs, Gastrointestinal Tract SCs, Pancreatic SCs, Hepatic Oval Cells, Mammary and Prostatic Gland SCs, Ovarian and Testicular SCs ![]() Their features can be similar to the natural embryo stem cells. In the medicine applications, the induced pluripotent stem cells (iPS) reveal a special significance, as they can be induced to derive from many adult tissues or organs by treatment of protein factors. The new understanding of stem cell has been applied to treat leukemia (induced differentiation) and bone/blood cancer (bone marrow transplants) for many years and has achieved great success. This concept has a great impact on the strategy of cancer chemotherapy and anti-cancer drug design. Based on current researches, adult stem cells appear to have a more restricted ability of producing different cell types and self-renewing compared with embryonic stem cells.Ĭancer stem cells are a sub-group of cancer cells that respond the escaping of cancer chemotherapy and the relapse of tumors. Adult stem cells are partially differentiated cells found among specialized (differentiated) cells in a tissue or organ. Embryonic cells derived from the part of a human embryo or fetus, are stem cells also with full potential to differentiation. Gametes cells (eggs or sperms) are stem cells they will develop to a whole body with various tissues after fertilizing. ![]() There are many types of stem cells, differing in their degree of differentiation and ability to self-renewing. The study of stem cells turns to be a major frontier in 21 century biology and medicine. In the battle to fight against diseases, stem cells present potencies to repair tissues by cell therapy and tissue regeneration. In science, it is still a challenge to understand how a fertilized egg to develop germ layers and various types of cells, which further develop to multiple tissues and organs with different biological functions. Stem cells are a group of cells in our bodies, with capacity to self-renew and differentiate to various types of cells, thus to construct tissues and organs. ![]()
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